2010年6月18日 星期五

AgeLOC Inside Nutrition Supplement Experience

Joe Chang Taking ageLOC Inside

Joe Chang, chief scientific officer of Nu Skin, recently conducted a test on himself and the new ageLOC supplement candidate. See how his gene expression profile was influenced after having taken Nu Skin's innovative ageLOC technology into the body.

2010年6月2日 星期三

What do genes have to do with ageLOC?


Mark Bartlett - Vice President Global Research & Development

We’ve heard a lot about aging lately in the media. In the past two months, both US News and World Report and Time Magazine have reported on a surprising new insight connecting genes and aging. These news organizations are now reporting what Nu Skin has known for some time - that our genes can be positively influenced and we can affect the way we age. By leveraging 30 years of genomic research, Nu Skin has placed itself in front of this scientific trend and is a clear leader in the industry.

The path leading up to our ageLOC science is quite interesting. Since James Watson, Francis Crick and Rosalind Franklin discovered the structure of DNA in 1953, the field of genetics has been advancing at an amazing rate. By 2003, the entire human genome had been sequenced, or decoded. From this advancement, we now know that humans have somewhere between 20,000 and 30,000 genes. About one tenth of those genes are involved in the regulation of expression of the rest. Our work today is to better understand how gene expression changes with age and how to externally influence it.

The latest technologies are making this task much more feasible. Now, on a single silicone chip about an inch square, we can measure the work output of a single gene in any tissue. By measuring this “work output,” we can track whether the created proteins are structural, like the collagen or the elastin in your skin, or enzymes, which catalyze all of the biochemical reactions that take place in your body. Therefore, we are now capable of measuring the aging process at the genetic level, and determining how external factors affect this process.

Simply put, we are now influencing aging at the genetic level. This is actually quite a liberating concept, and it’s not just hype. It turns out that whereas we’ve been focusing on the DNA as the hardwired brain, or computer of the cell, we haven’t been considering the software portion of the equation. It’s this influencing of the “software” that sets Nu Skin apart with ageLOC science.

This is an amazing breakthrough, and Nu Skin is positioned to take advantage of these developments to provide a new platform of anti-aging products today and well into the future.

Landmark Study on Tegreen 97 and Aging

Findings Show Strong Relationship Between Nutrition and Appearance



A recent clinical study showed that Pharmanex Tegreen 97 can actually enhance the appearance of skin.

A couple years ago, scientists from both Stanford School of Medicine and Nu Skin wanted to find the long-term effects of green tea on specific characteristics of facial skin. For two years, the scientists randomly administered Tegreen 97 or a placebo to 56 women two times a day. The women’s skin was then tested at six-, 12- and 24-month intervals.

The randomized, double-blinded, placebo-controlled study, the largest of its kind to date, revealed a strong correlation between Nu Skin’s Tegreen 97 and reductions in skin damage based on different study assessments, including grading from board-certified dermatologists.

In fact, 47% of women who took Tegreen 97 twice daily for two years had moderate or greater improvements in photoaging when compared to placebo. Additional significant self-assessments over baseline included:
- Reduction in pore size at 12 months
- Increased skin evenness at 12 months

Clinical graders reported the following significant improvements over baseline:
- Reduced appearance of small blood vessels (telangiectasias) on the skin’s surface at six and 12 months
- Reduced solar damage at six months



Joe Chang said, “This landmark research confirms Nu Skin’s philosophy that there is a strong relationship between nutrition and physical appearance. The results from this clinical study illustrate to consumers that the best anti-aging strategy requires a two-pronged approach that focuses on both internal nutrition and external skin care.”

Green tea has been used traditionally in China for thousands of years for its health-preserving and revitalizing power, and modern science has identified polyphenols as powerful antioxidants. One group of polyphenols—catechins—is particularly potent and highly effective in neutralizing free radicals at the cellular level. Tegreen 97 from Nu Skin contains a proprietary green tea extract containing 97 percent polyphenols of which 65 percent are catechins. The antioxidant power in one Tegreen 97 capsule is equivalent to seven cups of the traditionally brewed green tea drink and is 99.5 percent caffeine free.



In addition to the Tegreen 97 ingestible supplement, Nu Skin also includes Tegreen 97 in its topical Tru Face Essence Ultra firming serum as part of an antioxidant network to protect rejuvenated skin cells and proteins.

To learn more about the landmark study, click here.